Anemia in newly diagnosed cases with liver cirrhosis
DOI:
https://doi.org/10.2478/AMB-2025-0001Keywords:
Child-Pough, hemoglobin level, MCV, MELD NaAbstract
Between 50% and 87% of cases with liver cirrhosis have a concomitant anemic syndrome, which is the most common hematological abnormality on routine examination. Aim: To determine the frequency, type and severity of anemia in newly diagnosed cases
with liver cirrhosis. Materials and methods: A retrospective study of newly diagnosed cases of liver cirrhosis was performed for the period 2017–2021. The study group included 361 individuals, of whom 258 (71%) were men and 103 (29%) women. The mean age
was 57 ± 11.4 years. The main etiology was alcohol consumption in 262 (72.5%) of them. All were graded by Child-Pough score. MELD Na of each was calculated. Results were processed with IBM SPSS 26 and Excel statistics. We used ANOVA, Mann-Whitney, and
Pearson Chi-Square tests at a certain level of statistical dependence and a p-value less than 0.05. Results: Of the entire study population, 258 (71%) were found to be anemic, and mild anemia was found in 160 (62%) of them. The most common was normocytic anemia in 135 (52.3%) of the cases. Macrocytic anemia was found in 88 (34.1%) of the cases, which shows a significant dependence on alcohol etiology. Microcytic anemia was found in 35 (13.56%) of the cases. We confirmed a statistically significant difference in Child-Poug score (p = .000) and MELD Na score (p = .002) in cases without and with anemia. Conclusion: Anemia is the most common hematological manifestation in liver cirrhosis.
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