Describing adult heart failure patients – assessment of real-life data in two sites

Authors

  • I. Petrov Acibadem City Clinic Cardiovascular Center – Sofia, Bulgaria Author
  • V. Konstantinov Acibadem City Clinic Cardiovascular Center – Sofia, Bulgaria Author
  • L. Dosev City Clinic "Sv. Georgi" – Montana, Bulgaria Author
  • M. Jekov Sqilline Bulgaria – Sofia, Bulgaria Author
  • D. Penchev Sqilline Bulgaria – Sofia, Bulgaria Author
  • K. Genkova Novartis Bulgaria EOOD – Sofia, Bulgaria Author

DOI:

https://doi.org/10.2478/AMB-2024-0046

Keywords:

cardiology, treatment, heart failure, artificial intelligence

Abstract

Background. There is a lack of local clinical epidemiological data describing the different heart failure (HF) phenotypes in Bulgaria. Objective: Our goal was to describe the demographic and clinical characteristics of patients with HF in two cardiological hospitals.
The primary objective was to describe the demographic and clinical characteristics of patients with HF in two cardiological hospitals. The secondary objective was to further specify the profile of chronic HF patients by describing HF phenotype and the current treatment patterns of hospitalized patients. Primary and secondary outcome measures corresponding to the objectives
were descriptive in nature. Methods. This was a retrospective non-interventional study based on secondary anonymous pooled database analyses on management of patients with HF. The retrospective data was provided by Sqilline’s Danny Platform® – analytics AI (Artificial Intelligence) platform for real-world data. Results. The total number of patients with heart failure as main diagnosis or as comorbidity, or heart failure patients, treated on outpatient basis was 1313 (8%) as of 31th of March, 2019. The number of patients with heart failure as main diagnosis in the inpatient care was 413. The mean age of the patients was 69.77 years and more than 50% of hospitalized patients were males. Ejection fraction was available in 352 HF patients in the inpatient care as follows: 40-49% in 48 patients, less than 40% in 67 patients and more than 50% in 240 patients. The most frequently observed comorbidity in hospitalized patients with two or more comorbidities (66.1%) was as follows: hypertensive heart disease with heart failure (78.0%), atrial fibrillation and flutter (42.1%). Conclusions. We succeeded in describing the demographic and clinical characteristics of 413 HF patients in Bulgaria. Digitalization in healthcare is an unmet need which should be addressed on a broad societal scale requiring all stakeholders to be involved.

References

McMurray JJ, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The task force for the diagnosis and treatment of acute and chronic heart failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J; 2012. 33(14): 1787-847. doi: 10.1093/eurheartj/ehs104

Movsisyan Narine K, et al. Cardiovascular diseases in Central and Eastern Europe: a call for more surveillance and evidence-based health promotion. Annals of Global Health, U.S. National Library of Medicine; 26 Feb. 2020. doi: 10.5334/aogh.2713

Watson R. Heart disease rising in Central and Eastern Europe. BMJ (Clinical Research Ed.), U.S. National Library of Medicine; 19 Feb. 2000. doi: 10.1136/bmj.320.7233.467

Borlaug BA, Paulus WJ. Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment. Eur Heart J; 2011. 32(6): p. 670-9. doi: 10.1093/eurheartj/ehq426.

Krum H, Gilbert RE. Demographics and concomitant disorders in heart failure. Lancet; 2003. 362(9378): 147-58. doi: 10.1016/S0140-736(03)13869-X.

Gerber Y, et al. A contemporary appraisal of the heart failure epidemic in Olmsted County, Minnesota, 2000 to 2010. JAMA

Intern Med; 2015. 175(6): 996-1004. doi: 10.1001/jamainternmed.2015.0924.

Holland R, et al. Patients’ self-assessed functional status in heart failure by New York Heart Association class: a prognostic predictor of hospitalizations, quality of life and death. J Card Fail; 2010. 16(2): 150-6. doi: 10.1016/j.cardfail.2009.08.010.

Lopatin Y. Heart failure with mid-range ejection fraction and how to treat it. Card Fail Rev; 2018. 4(1): 9-13. doi: 10.15420/cfr.2018:10:1

Lindmark K, et al. Epidemiology of heart failure and trends in diagnostic work-up: a retrospective, population-based cohort study in Sweden. Clin Epidemiol; 2019. 11: 231-244. doi: 10.2147/CLEP.S170873.

Tian J, et al. Analysis of re-hospitalizations for patients with heart failure caused by coronary heart disease: data of first event and recurrent event. Ther Clin Risk Manag; 2019. (15): 1333-1341. doi: 10.2147/TCRM.S218694

Fudim M, et al. Aetiology, timing and clinical predictors of early vs. late readmission following index hospitalization for acute heart failure: insights from ASCEND-HF. Eur J Heart Fail; 2018. 20(2): 304-314. doi: 10.1002/ejhf.1020.

Maggioni AP, et al. EURObservational research programme: regional differences and 1-year follow-up results of the heart failure pilot survey (ESC-HF Pilot). Eur J Heart Fail; 2013. 15(7): 808-17. doi: 10.1093/eurjhf/hft050.

Dunlay SM, et al. Type 2 diabetes mellitus and heart failure: a scientific statement from the American Heart Association and the Heart Failure Society of America: This statement does not represent an update of the 2017 ACC/AHA/HFSA heart failure guideline update. Circulation; 2019,140(7): e294-e324. doi: 10.1161/CIR.0000000000000691.

1AA. Heart failure with mid-range ejection fraction: A review of clinical status and meta-analysis of clinical management methods. Trends in Res 1; 2018. doi: 10.15761/

TR.1000121

Downloads

Published

04.10.2024

How to Cite

Petrov, I., Konstantinov, V. ., Dosev, L., Jekov, M., Penchev, D., & Genkova, K. (2024). Describing adult heart failure patients – assessment of real-life data in two sites. Acta Medica Bulgarica, 51(Suppl 2), 1-12. https://doi.org/10.2478/AMB-2024-0046