Comparative evaluation of two surgical approaches for the regenerative treatment of intrabony periodontal bone defects

Authors

  • H. Maynalovska Department of Periodontology, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria Author https://orcid.org/0000-0001-8331-1514
  • V. Dosseva-Panova Department of Periodontology, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria Author
  • A. Mlachkova Department of Periodontology, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria Author
  • Z. Pashova-Tasseva Department of Periodontology, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria Author
  • I. Ivanov Department of Periodontology, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria Author
  • K. Kotsilkov Department of Periodontology, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria Author

DOI:

https://doi.org/10.2478/AMB-2026-0003

Keywords:

minimally invasive periodontal surgery, periodontal regeneration, papilla elevation, vertical bone defects

Abstract

Abstract. This study aimed to evaluate the influence of two minimally invasive surgical protocols – with different approaches to papilla management – on regenerative outcomes achieved using enamel matrix derivative in combination with bone grafts. Materials and Methods: Two treatment groups were analyzed, comprising a total of 19 patients diagnosed with advanced periodontitis. Group 1 included 11 patients contributing 14 vertical bone defects, treated with a combination of enamel matrix derivative (EMD) and xenograft. Group 2 consisted of 8 patients, also with 14 vertical defects, treated with EMD and allograft. The comparison between the two groups was based on three clinical parameters assessed at the 6-month follow-up: residual probing pocket depth, clinical attachment gain, and residual bone defect depth. The Shapiro–Wilk test was used to assess data distribution. Depending on normality and variance, intergroup comparisons were performed using either the Mann–Whitney U test or Welch’s t-test. Results: Both treatment groups demonstrated similar clinical improvements at 6 months, with no statistically significant differences in residual probing pocket depth, clinical attachment gain, or residual bone defect depth. Conclusion: At the 6-month follow-up, both minimally invasive surgical approaches yielded comparable clinical and radiographic outcomes. Further long-term studies are warranted to assess the potential emergence of differences in soft tissue stability and clinical parameters over time.

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Published

06.02.2026

How to Cite

Maynalovska, H., Dosseva-Panova, V., Mlachkova, A., Pashova-Tasseva, Z., Ivanov, I., & Kotsilkov, K. (2026). Comparative evaluation of two surgical approaches for the regenerative treatment of intrabony periodontal bone defects. Acta Medica Bulgarica, 53(Suppl 1), 24-29. https://doi.org/10.2478/AMB-2026-0003