Sleep disturbances after endocrine therapy in women with breast cancer

Authors

  • Iv. Ivanova Department of Medical Oncology, UMHAT “Dr Georgi Stranski” – Pleven; Department of Social Medicine and Health Management, Faculty of Public Health, Medical University – Pleven Author
  • S. Tsvetkova Section of Preclinical and Clinical Sciences, Faculty of Pharmacy, Medical University – Pleven Author
  • M. Kamburova Department of Social Medicine and Health Management, Faculty of Public Health, Medical University – Pleven Author

Keywords:

breast cancer, sleep disorder, quality of life

Abstract

Introduction: Endocrine therapy is a standard treatment for women with breast cancer. It can cause sleep disturbances that affect women's normal functioning. Objective: The aim of the present study is to analyze the results of the questions related to sleep disturbances and the results of the physical, role and emotional functioning scales in women with breast cancer undergoing hormonal therapy. Materials and Methods: The results of 210 women are presented. A demographic questionnaire and a quality of life questionnaire were used. Excel and SPSS v26 were used for statistical analysis and data processing. Results and Discussion: Over 2/3 of the respondents reported sleep disorders – 72%. A moderate correlation was found between the results for sleep problems and physical function at (r = 0.358, p = 0.000); insomnia and poor sleep quality adversely affect the performance of normal daily activities. A moderate correlation was observed between sleep disorders and emotional function (r = 0.349, p = 0.000). Sleep problems correlated moderately with role functioning (r = 0.343, p = 0.000). Conclusion: Sleep disturbance is a serious challenge for women undergoing hormonal therapy for breast cancer. Timely assessment of insomnia symptoms is necessary to gain an understanding of the problem and implement the necessary therapy.

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Published

28.04.2026

How to Cite

Sleep disturbances after endocrine therapy in women with breast cancer (I. Ivanova, S. Tsvetkova, & M. Kamburova , Trans.). (2026). Bulgarian Medical Journal, 20(1), 43-48. https://journals.mu-sofia.bg/index.php/bmj/article/view/799

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