Application of LAMP as a point-of-care diagnostic assay in remote and low-income regions: mini-review
DOI:
https://doi.org/10.2478/AMB-2024-0020Keywords:
LAMP, point-of-care, diagnosticsAbstract
Loop-mediated isothermal amplification (LAMP) has received increased attention as a sensitive and fast molecular technique that could be applied at the site of need. The LAMP has been shown to specifically detect a variety of bacterial and viral infections as a promising point-of-care (POC) test. LAMP has recently demonstrated sensitivity and specificity comparable to or nearly equal to polymerase chain reaction in SARS-CoV-2 detection. The main advantages of LAMP are its application in low-income or remote areas
where there are no specialized laboratories or molecular specialists. In the following minireview we discuss the potential of LAMP as a POC molecular diagnostic method. Moreover, we summarized its validated application and future challenges.
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