Съвременни аспекти в диагностиката и лечението на сепсиса

Fleischmann-Struzek C, Rudd K. Challenges of assessing the burden of sepsis. Med Klin Intensivmed Notfmed, 2023, 118(Suppl 2):68-74.

Rudd KE, Johnson SC, Agesa KM, et al. Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study. Lancet, 2020, 395(10219):200-211.

Arefian H, Heublein S, Scherag A, et al. Hospital-related cost of sepsis: A systematic review. J Infect, 2017, 74(2):107-117.

Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA, 2016, 315(8): 801-810.

Seymour CW, Liu VX, Iwashyna TJ, et al. Assessment of Clinical Criteria for Sepsis: for the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) [published correction appears in JAMA. 2016; 315(20): 2237]. JAMA, 2016, 315(8): 762-774.

Gupta S, Sakhuja A, Kumar G, et al. Culture-negative severe sepsis: nationwide trends and outcomes. Chest, 2016, 150(6):1251-1259.

Mayr FB, Yende S, Angus DC. Epidemiology of severe sepsis. Virulence, 2014, 5(1):4-11.

Angus DC, van der Poll T. Severe sepsis and septic shock [published correction appears in N Engl J Med, 2013, 369(21):2069]. N Engl J Med. 2013; 369(9):840-851.

Nannan Panday RS, Lammers EMJ, Alam N, et al. An overview of positive cultures and clinical outcomes in septic patients. Crit Care, 2019, 23(1):182.

Pakov I. Immune reconstitution in late-presenting HIV-positive case with idiopathic liver cirrhosis and ischemic brain stroke. JBCR, 2023, 16(1):66-73.

Паков И, Дойчинова Ц. HIV-асоциирана смъртност и причини за настъпването ѝ при късно представящи се пациенти. Мединфо, 2020, (3), 58-62. [Pakov I, Doychinova T. HIV-associated mortality and causes of its occurrence in late-presenting patients. Medinfo, 2020, (3), 58-62.]

Cecconi M, Evans L, Levy M, et al. Sepsis and septic shock. Lancet, 2018, 392(10141):75-87.

Gotts JE, Matthay MA. Sepsis: pathophysiology and clinical management. BMJ, 2016, 23:353:i1585.

Antimicrobial Resistance Collaborators. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet, 2022, 399(10325):629-655.

Fleischmann C, Scherag A, Adhikari NK, et al. International Forum of Acute Care Trialists. Assessment of global incidence and mortality of hospital-treated sepsis. Am J Respir Crit Care Med, 2016, 193(3):259-272.

Cunha BA. Sepsis and septic shock: selection of empiric antimicrobial therapy. Crit Care Clin, 2008, 24(2):313-334, ix.

Dongkwan H, Seung HK, Young WU, et al. Temperature trajectories and mortality in hypothermic sepsis patients. Am J Emerg Med, 2024, 84:18-24.

National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network; Shapiro NI, Douglas IS, Brower RG, et al. Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension. N Engl J Med. 2023, 388(6):499-510.

Rumbus Z, Matics R, Hegyi P, et al. Fever is associated with reduced, hypothermia with increased mortality in septic patients: a meta-analysis of clinical trials. PLoS One, 2017, 12(1):e0170152.

White HD, Vazquez-Sandoval A, Quiroga PF, et al. Utility of venous blood gases in severe sepsis and septic shock. Proc (Bayl Univ Med Cent), 2018, 31(3):269-275.

Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock: 2016. Crit Care Med, 2017, 45(3):486-552.

Vijayan AL, Vanimaya, Ravindran S, et al. Procalcitonin: a promising diagnostic marker for sepsis and antibiotic therapy. J Intensive Care, 2017, 5:51.

Yunus I, Fasih A, Wang Y. The use of procalcitonin in the determination of severity of sepsis, patient outcomes and infection characteristics. PLoS One, 2018, 13(11):e0206527.

Velissaris D, Zareifopoulos N, Lagadinou M, et al. Procalcitonin and sepsis in the Emergency Department: an update. Eur Rev Med Pharmacol Sci, 2021, 25(1):466-479.

Weinberger J, Klompas M, Rhee C. What Is the Utility of Measuring Lactate Levels in Patients with Sepsis and Septic Shock? Semin Respir Crit Care Med, 2021, 42(5):650-661.

Ryoo SM, Lee J, Lee YS, et al. Lactate level versus lactate clearance for predicting mortality in patients with septic shock defined by Sepsis-3. Crit Care Med, 2018, 46(6):e489-e495.

McIntyre L, Rowe BH, Walsh TS, et al.; Canadian Critical Care Trials Group. Multicountry survey of emergency and critical care medicine physicians’ fluid resuscitation practices for adult patients with early septic shock. BMJ Open, 2016, 6(7):e010041.

Semler MW, Self WH, Wanderer JP, et al.; SMART Investigators and the Pragmatic Critical Care Research Group. Balanced crystalloids versus saline in critically ill adults. N Engl J Med, 2018, 378(9):829-839.

Long B, Koyfman A, Modisett KL, et al. Practical considerations in sepsis resuscitation. J Emerg Med. 2017; 52(4): 472-483.

Brown RM, Semler MW. Fluid management in sepsis. J Intensive Care Med, 2019, 34(5):364-373.

Sherwin R, Winters ME, Vilke GM, et al. Does early and appropriate antibiotic administration improve mortality in emergency department patients with severe sepsis or septic shock? J Emerg Med, 2017, 53(4):588-595.

Rhee C, Chen T, Kadri SS, et al.; CDC Prevention Epicenters Program. Trends in Empiric Broad-Spectrum Antibiotic Use for Suspected Community-Onset Sepsis in US Hospitals. JAMA Netw Open. 2024, 7(6):e2418923.

Whiles BB, Deis AS, Simpson SQ. Increased time to initial antimicrobial administration is associated with progression to septic shock in severe sepsis patients. Crit Care Med, 2017, 45(4):623-629.

Seymour CW, Kahn JM, Martin-Gill C, et al. Delays from first medical contact to antibiotic administration for sepsis. Crit Care Med. 2017, 45(5):759-765.

Levy MM, Rhodes A, Evans LE. Steering and Executive Committee of the Surviving Sepsis Campaign. Counterpoint: should the surviving sepsis campaign guidelines be retired? No. Chest, 2019, 155(1):14-17.

Sterling SA, Miller WR, Pryor J, et al. The impact of timing of antibiotics on outcomes in severe sepsis and septic shock: a systematic review and meta-analysis. Crit Care Med. 2015; 43(9): 1907-1915.

Peltan ID, Brown SM, Bledsoe JR, et al. ED door-to-antibiotic time and long-term mortality in sepsis. Chest, 2019,155(5):938-946.

Kalil AC, Metersky ML, Klompas M, et al. Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious

Diseases Society of America and the American Thoracic Society [published corrections appear in Clin Infect Dis. 2017; 64(9): 1298, Clin Infect Dis. 2017; 65(8): 1435, and Clin Infect Dis. 2017; 65(12): 2161]. Clin Infect Dis, 2016, 63(5):e61-e111.

Rhee C, Kadri SS, Dekker JP, et al.; CDC Prevention Epicenters Program. Prevalence of Antibiotic-Resistant Pathogens in Culture-Proven Sepsis and Outcomes Associated With Inadequate and Broad-Spectrum Empiric Antibiotic Use. JAMA Netw Open, 2020, 3(4):e202899.

Kollef MH, Shorr AF, Bassetti M, et al. Timing of antibiotic therapy in the ICU. Crit Care, 2021, 25(1):360.

Coggins SA, Glaser K. Updates in Late-Onset Sepsis: Risk Assessment, Therapy, and Outcomes. Neoreviews, 2022, 23(11):738-755.

Levy MM, Evans LE, Rhodes A. The surviving sepsis campaign bundle: 2018 update. Intensive Care Med, 2018, 44(6):925-928.

Bai X, Yu W, Ji W, et al. Early versus delayed administration of norepinephrine in patients with septic shock. Crit Care, 2014, 18(5): 532.

Kalimouttou A, Kennedy JN, Feng J, et al. Optimal Vasopressin Initiation in Septic Shock: The OVISS Reinforcement Learning Study. JAMA, 2025, 333(19):1688-1698. Erratum in: JAMA. 2025 May 6;333(17):1549.

Permpikul C, Tongyoo S, Viarasilpa T, et al. Early use of norepinephrine in septic shock resuscitation (CENSER): a randomized trial. Am J Respir Crit Care Med, 2019, 199(9):1097-1105.

Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Critical Care Medicine, 2021, 49(11):p e1063-e1143.

Chaudhuri D, Nei A, Rochwerg B, et al. 2024 Focused Update: Guidelines on Use of Corticosteroids in Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia. Critical Care Medicine, 2024, 52(5):e219-e233.

Marik PE, Khangoora V, Rivera R, et al. Hydrocortisone, vitamin C, and thiamine for the treatment of severe sepsis and septic shock: a retrospective before-after study. Chest, 2017, 151(6):1229-1238.

Rubin R. Wide interest in a vitamin C drug cocktail for sepsis despite lagging evidence. JAMA, 2019, 322(4):291-293.

Seymour CW, Kennedy JN, Wang S, et al. Derivation, validation, and potential treatment implications of novel clinical phenotypes for sepsis. JAMA, 2019, 321(20):2003-2017.