Hypopyon keratitis as a complication of primary varicella in a 7-month-old child

Authors

  • V. Marinov Department of Ophthalmology, Medical Faculty, Medical University – Plovdiv, Bulgaria Author https://orcid.org/0000-0002-3246-8906
  • K. Slaveykov Department of Internal Diseases and General Medicine, Medical Faculty, Trakia University – Stara Zagora, Bulgaria Author https://orcid.org/0000-0001-7718-8839
  • K. Trifonova Department of Ophthalmology and Otorhinolaryngology, Medical Faculty, Trakia University – Stara Zagora, Bulgaria Author

DOI:

https://doi.org/10.2478/AMB-2025-0015

Keywords:

bacterial keratitis, chickenpox, ocular complications

Abstract

Ocular complications associated with primary varicella zoster virus infection may involve any part of the eye. Unlike ophthalmic zoster in which the virus reactivates, ocular complications from primary varicella are rare. The aim is to present an interesting clinical case of a primary varicella keratitis overlapped by a bacterial infection. A seven-month old boy was presented to an outpatient clinic 10 days (about 1 and a half weeks) after the beginning of a chickenpox rash with symptoms of bacterial keratitis of his right eye. He was admitted to a specialized clinic and successfully treated with a combination of topical quinolone treatment, washing of the conjunctival sac with iod-povidone 5% and two subconjunctival applications of Cefotaxime 5% and Atropine/Adrenalin 1% under general anesthesia. Twenty days after the initial complaints there were no signs of inflammation and only two small macules could still be observed. The child would be followed up for three months in case of recurrence. Primary varicella, even though considered benign in childhood, should not be underestimated. Some serious ocular complications can develop which if left untreated could lead to devastating visual results.

Author Biographies

  • V. Marinov, Department of Ophthalmology, Medical Faculty, Medical University – Plovdiv, Bulgaria

    Department of Ophthalmology, PhD, MD

  • K. Slaveykov, Department of Internal Diseases and General Medicine, Medical Faculty, Trakia University – Stara Zagora, Bulgaria

    Department of Internal Diseases and General Medicine 

References

Boyd G, Heaton P, Wilkinson R, et al. Nursing management of childhood chickenpox infection. Emerg Nurse, 2017, 25(8), 32-41.

Kaufman S. Anterior segment complications of herpes zoster ophthalmicus. Ophthalmology. 2008, 115: S24–S32.

De Castro L, Al Sarraf O, Hawthorne K, et al. Ocular manifestations after primary varicella infection. Cornea. 2006, 25(7):866–867.

Gargouri S, Khochtali S, Zina S, et al. Ocular involvement associated with varicella in adults. J Ophthalmic Infl amm Infect. 2016, 6(1):47.

Yap A, Sims J, Niederer. Ocular complications from primary varicella infection. Mass masking: an, 2020, 133,1517.

Farooqui A, Tahir M, Jaiswal A, et al. Oculomotor palsy following varicella in an immunocompetent adult. South Med J. 2009, 102(4):445.

Loewenstein A. Specifi c infl ammation of the cornea in chickenpox. Br J Ophthalmol. 1940, 24(8):391.

Denier M, Gabison E, Sahyoun, M, et al. Stromal Keratitis After Varicella in Children. Cornea, 2020, 39(6), 680–684.

Bozzola E, Marchesani S, Ficari A. et al. Assessing the use of antibiotics in pediatric patients hospitalized for varicella. Ital J Pediatr, 022, 48(1):196.

Pedro-Egbe C, Chukwuka I, Fiebai B, et al. Eye Complications of Chicken Pox in Port Harcourt Nigeria: Report of 4 Cases. J Ophthalmic Clin Res, 2019, 6, 047.

Garg P, Mathur U, Athmanathan S, Rao GN. Treatment outcome of Moraxella keratitis: our experience with 18 cases – a retrospective review. Cornea. 1999, 18(2):176-81.

Ozcan G, Temel E, Yalcindag N, et al. Chickenpox Associated Retinitis and Occlusive Vasculitis in a Vaccinated Child: A Case Report and Literature Review. Beyoglu Eye J. 2022, 27;7(2):143-149.

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Published

30.04.2025

How to Cite

Marinov, V., Slaveykov, K., & Trifonova, K. (2025). Hypopyon keratitis as a complication of primary varicella in a 7-month-old child. Acta Medica Bulgarica, 52(Suppl 1), 1-4. https://doi.org/10.2478/AMB-2025-0015